On Gladius Prime, a planet once thriving with life, war has consumed all. Various factions, including Orks, Necrons, Space Marines, and the Astra Militarum, struggle for dominance. Yet, an even greater threat has emerged from the shadows: the Feral Tyranids, dreadful escapees from an Imperial research facility, now roam freely across the scarred landscape. In Warhammer 40,000: Gladius - Tyranids, players encounter a new playable race that brings unique gameplay mechanics, setting them apart from existing factions.

The Tyranids, known as the Great Devourer, are an insatiable swarm, seeking to consume Gladius Prime. This faction specializes in reclaiming biomass from defeated enemies and the environment, utilizing this energy to evolve and reproduce at an alarming rate. The Hive Mind, a vast psychic network, controls the Tyranid units, ranging from the ferocious Hormagaunts to the terrifying Tyrants, each adapted through the consumption of their foes. As they advance, the Tyranids bring a relentless and dynamic playstyle that challenges players to strategize and adapt continuously, for stillness equates to death in the face of their overwhelming hunger.