Sakura Forest Girls 2 is an enchanting Visual Novel that follows the journey of childhood friends Yaya and Aiyana, who are on a quest to find their missing friend Koko. Their tranquil village life is shattered when mysterious monsters attack, leading to Koko's disappearance. Three years later, fueled by determination and hope, Yaya and Aiyana set out to rescue her.

To aid them, they enlist the help of the mischievous witch, Maia, whose magical abilities can uncover Koko’s whereabouts. Their adventure brings them to a neighboring village plagued by drought, ruled by the kind yet inexperienced princess, Arie. While assisting Arie in her desperate plight, a bond begins to form between her and Yaya, complicating their mission.

As they navigate friendships and navigate challenges, Yaya's affinity for hunting and Aiyana’s innate struggles against her anxious nature come to light. With the cunning Maia's antics adding a layer of humor and intrigue, the quest spirals into moral dilemmas and personal growth. With time running out, Yaya must decide between her heart’s desire and her loyalty to her friends. Will they uncover the truth behind Koko's disappearance and restore balance to both villages?